Transient Thyrotoxicosis in Molar Pregnancy

Gestational transient thyrotoxicosis.

Gestational transient thyrotoxicosis refers to non-autoimmune hyperthyroidism in pregnant women and it is associated with hyperemesis gravidarum. During pregnancy, there are some alterations in thyroid gland, such as elevation of thyroxine binding globulin, increased iodium clearance in kidneys, and stimulation of thyroid gland by human chorionic gonadotropin. Hitherto, the pathophysiology unde...

Molar Pregnancy Causing Thyrotoxicosis in a Teenage Girl With Type 1 Diabetes Mellitus

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Thyrotoxicosis and pregnancy

Thyrotoxicosis affects 1-3.5% of all pregnancies and its major cause is gestational hyperthyroidism and Graves’ disease, less common – multinodular toxic goiter and toxic adenoma, and rare – subacute or silent thyroiditis and struma ovarii. Gestational hyperthyroidism is a transient form of thyrotoxicosis caused by excessive stimulation of thyroid gland by hCG and usually limited to the first 1...

Molar Pregnancy Presents as Tubal Ectopic Pregnancy

Thyrotoxicosis and Pregnancy

A 35-year-old woman became aware of a swelling in her neck about ten weeks before referral. She had been trying to conceive for ten months. She had had a missed abortion fi ve months earlier. Because of the neck swelling, her family doctor arranged thyroid function tests, which were in the thyrotoxic range on two occasions fi ve weeks apart: serum free thyroxine, 26 and 28 pmol/l (normal range,...